Proton pump inhibitor (PPI) medications are commonly prescribed to individuals with heartburn and acid reflux disease. These drugs work by blocking acid buildup in the stomach. However, they also inhibit the absorption of vital minerals, which may lead to serious side effects including chronic kidney disease (CKD), heart attack, bone fractures and more.


Recent research studies identified that proton pump inhibitor medications like Nexium, Prevacid, Prilosec and others that are used to control stomach acid could actually increase patient’s risk of chronic kidney disease. FrancoLaw is investigating lawsuits involving Nexium, Prilosec, and Prevacid and chronic kidney disease and other serious kidney injuries. If you or a loved one took one of these medications and suffered a serious kidney injury or developed kidney disease, contact us for a free case review at 1.888.213.0761.


In 2016, the Journal of the American Medical Association (JAMA) published a study which found that long-term usage of Nexium, Prilosec and Prevacid could increase the risk of the development of chronic kidney disease (CKD). Furthermore, the study showed that the risk of CKD in PPI users over a ten-year period was 20 to 50 percent higher than those who did not take the medications.


Another study presented at the American Society of Nephrology meeting in 2015 shared similar outcomes and indicated that the longer that the patient was taking medication, the higher the risk might be. These results followed a previous study which indicated that patients taking PPI medications like Nexium or Prilosec could have up to a 21% higher risk for heart attack or myocardial infarction.


These research studies are linked to others that have connected PPI usage to adverse events like bone fractures and hypomagnesemia. According to observational studies performed by the U.S. Food and Drug Administration (FDA), use of proton pump inhibitors increased risk of hip, wrist, and spine fractures among individuals aged 50 years and older. The greatest increased risk involved people who were taking PPIs for at least 1 year or those who had received high doses at regular internals. Furthermore, there was a clear association where the population had a previous risk for potential fracture.


PPIs may also be linked to acquired infections, birth defects and acute kidney infections. A 2015 study found that older patients who took PPIs were twice as likely to be hospitalized with kidney failure than those who didn’t take the medication. PPIs have recently been linked to a higher risk for cognitive problems, too. A new German study in 2016 identified that those patients at least aged 75 who tooks PPIs like Prilosec and Nexium had a 44 percent higher risk of developing dementia. Unfortunately, the majority of the most popular heart burn medications in America today are proton pump inhibitors including Prilosec, Prevacid, and Nexium.





When your doctor prescribes you a drug like Prevacid, Prilosec, or Nexium, you expect that it will help you with your medical condition rather than putting you at risk for something more serious. Sadly, too many patients have paid the price in terms of severe injuries. If you suspect that the medical impacts of taking one of these medications has changed your life, you may want to consider filing a lawsuit. For more information, or to speak with someone about your potential case, please call us toll-free at 1.888.213.0761 or fill out our free case review form. FrancoLaw is experienced in handling defective drug cases and we welcome any questions you may have.